IMITATION OF NATURE

To initiate & promote experimentation & innovations in the field of pharmaceutical chemistry, Luqman College of Pharmacy comprising of three pharmaceutical chemistry laboratory with enough space & basic necessity like electricity, water supply, gas supply, fuming chamber, Balance room, preparation room etc.

                        The department has been entrusted the task to provide result oriented practical education for students, Pharmaceutical chemistry laboratory provides & confers following subjects.

               1. Medicinal Chemistry I and II.

               2. Biochemistry

               3.Pharmaceutical Chemistry lab-I & II

               1. Pharmaceutical Organic Chemistry I & II

               2.Synthesis & Estimations.

              1.Pharmaceutical Analysis

              2.Pharmaceutical Chemistry-I (D.Pharm)

              3.Pharmaceutical Inorganic Chemistry

 

Our strengths are programs in Pharmaceutical Synthesis, Qualitative Estimation, Quantitative Estimation, Analytical Constants of Fats & Oils. Pharmaceutical Department plays a critical role in shaping, manufacturing & formulation interms structure activity relationship. This department is uniquely positioned to create value through recent developments in pharmaceutical research & other emerging technologies. Pharmacy students are required to learn acquire exhaustive knowledge of synthesis, Mode of action, Molecular Drug Design, Systematic Qualitative Analysis of unknown Organic Compound, Estimation, Identification, Quantitative Estimations. Carbohydrates test, Urine Analysis, Separation of Amino Acids by Chromatography Methods, Analytical Constants of Fats & Oils, Preparation of Paracetomol Drugs. Acytillation, Allcylation, Alkylation methods, Limit test, Colorimetric estimations many more programs of professional excellence.

 

FACILITY AVAILABLE:

The pharmaceutical chemistry department having adequate qualified & experienced staff. laboratories are well equipped with following instruments:

  1. Hot Air Oven

  2. Display Set of Atomic Models.

  3. Distillation Unit

  4. Physical Balances.

  5. Chemical Balances

  6. Electronic Digital Balances

  7. Vacuum Pump.

  8. Fuming Chamber.

  9. Triple Beam Balance.

  10. Polorimeter

  11. Deioniser Plant.

  12. PH.Meter

  13. Colorimeter.

  14. Flame Photometer (Digital)

  15. Nephelometer.

  16. Spectrophotometer.

  17. All Glass Distillation Set.

  18. Fire Extinguisher.

  19. Refrigerator.

  20. Various Display Charts.

  21. Rough Balance.

  22. Electronic Balance.

  23. Fluorometer.

  24. Digital Conductivity Meter.

  25. Melting Point Apparatus.

 

FACULTY POSITION

STAFF INFORMATION

 

NON-TEACHING

NAME  QUALIFICATION DESIGNATION
Mr.Anilkumar Maski B.Sc, D.Pharm Lab Technician
Mr.Syed Javeed   Lab Asst
Mr.Isha Khan   Lab Asst
Mr.Shafiq Patel   Lab Asst

 

 

The Pharmaceutical Chemistry Department has maintained high academic standard with 98% overall practical for the year 2004-05. Our departmental teams are working closely with an extensive network of practical, Converting the latest Research results into products & services for better tomorrow. We are committed to offering our students the best training available. We also encourage research & development, critical thinking skills & positive approach & belief.

 

EXERCISE

The Luqman College of Pharmacy & its wing dept of pharmaceutical chemistry provides following exercise for Pharmacy students:

  1. Estimation of Amines by Bromination Method.

  2. Estimation of Phenols by Bromination Method.

  3. Estimation of Citric Acid.

  4. Estimation of Carbohydrates by using Fehlings Solution.

  5. Estimation of Aminoacids by Formal titration Method.

  6. Estimation of  Esters. 

  7. Acid value determination of Fats & Oils.

  8. Soponification value of Determination.

  9. Iodine Number Determination.

  10. Preparation of P-Nitro Acetanilide.

  11. Preparation of Aspirin

  12. Preparation of Benzophenone Oxime.

  13. Qualitative Analysis of unknown Organic Compound.

  14. Identification Test for Streptomycin Drug.

  15. Osazone Preparation.

  16. Iodoform Preparation.

  17. Limit Test Experiment.

  18. Preparation of Salicylic Acid

  19. Preparation of P-Bromoacetanalide.

  20. Preparation of Benzoicacid by Oxidation Method.

 

 

Research Publications

       

        Dr. G. K. Kapse

        1.

 

 

        SUDHEENDRA GUBBI  

  1. R. H. Udupi, V. M. Kulkarni, Sudheendra, S. Ramachandra Setty, and P. Purushottamachar, “Synthesis and biological activity of some 1,2,4-triazoles and related heterocycles”.   Indian Journal of Heterocyclic chemistry, Vol.11, April-June 2002. pp 303-306.
  2. P. Srinivasa Rao, Sudheendra and R. H. Udupi, “Synthesis and Biological Evaluation of 3-(6’-methoxynaphth-2-yl)ethyl-4-substituted-5-mercapto-1,2,4-triazoles and thiadiazoles” Indian Journal of Heterocyclic Chemistry, Vol.15, Jan-March, 2006, pp 291-292.
  3. R. H. Udupi, Sudheendra, Bheemachari, N. Srinivasulu , Rajesh Varnekar and P. Purushottamachar, “Design, Synthesis and Biological Activity of certain 3,4-disubstituted-5-mercapto-1,2,4-triazoles and their hydrazino derivatives. Bull. Korean Chem. Soc. 2007, Vol. 28, No. 12, 2235.
  4. Sudheendra, P. Srinivas Rao and R.H. Udupi, “Synthesis and biological evaluation of certain new pyrazoline derivativesOriental Journal of Chemistry, Vol 23, No.1, 2007.
  5. Sudheendra, P. Srinivas Rao, Bheemachari, R. H. Udupi, S. Ramachandra Setty and Rajesh Varnekar , “ Synthesis and Evaluation of biological activities of 3-aryloxymethyl-7,7-dimethyl-5-pyrazinoyl-6,7,8,9-tetrahydro-1,2,4-triazolo(4,3-b) (4,1,2)-benzothiadiazin-9-ones”. Indian Journal of Heterocyclic Chemistry, Vol.17, July-Sept., 2007, pp 63-66.
  6. R. H. Udupi, Sudheendra, Bheemachari, N. Srinivasulu , Rajesh Varnekar and P. Purushottamachar, “Design, Synthesis and Biological Activity of certain 3,4-disubstituted-5-mercapto-1,2,4-triazoles and their hydrazino derivatives”. Bull. Korean Chem. Soc. 2007, Vol. 28, No. 12, 2235.
  7. Pramila T., Sudheendra, Bheemachari, N. Sreenivasulu and R.H. Udupi, “Synthesis and Biological Activity of Bridgehead Nitrogen Heterocycles: Reactions of 3-Aryloxymethyl-4-[N-pyrazin-2’-yl carboxamido]-5-mercapto-1,2,4-triazoles”. Indian Journal of Heterocyclic Chemistry, Vol.17, July-Sept., 2007, pp 63-66.

 

 

        M. H. HUGAR  

  1. Synthesis and Biological Evaluation of Benzofuro [3, 2-d] Pyrimidones. Raga Basawaraj, Goled Shashikanth, M.H.Hugar and S.S.Sangapure*  Indian Journal of Heterocyclic Chemistry, vol 18, April-June, 2009.pp 329-332.

  2. Synthesis, anlgesic and anti-pyretic activity of Pyrimidine derivatives containing a coumarin moiety. R.S.Keri, K.M.Hosamani* and M.H.Hugar.  European Journal of Medicinal Chemistry. 45 (2010) 2597-2605.  DOI: 10.1016/j.ejmech.2010.02.048, Elsevier Publication.

  3. Derivatives of  benzimidazole pharmacophore: Synthesis, anticonvulsant, Antidiabetic and DNA cleavage studies. R.V.Shingalapur, K.M.Hosamani*, R.S.Keri and M.H.Hugar

    European Journal of Medicinal Chemistry, 45 (2010) 1753–1759. DOI: 10.1016/j.ejmech.2010.01.007, Elsevier Publication.

  4. Phytochemical and pharmacological studies of ethanol extract of Dalbergia sissoo seeds: An approach for the In-vivo analgesic and antipyretic activities. Mallinath H. Hugar, Kallappa M. Hosamani* and Md Liyakath Ahmed International Journal of Pharma and Bio Sciences , 1(4),2010,272-280.

  5. In-vivo Anti-Diabetic and Anti-Convulsant Evaluation of 3-Benzo [4,5] Imidazo [2,1-b] Thiazol-3-yl-Chromen-2-One Derivatives Harisha R.S., *Hosamani K.M. and  Hugar M.H.

    Journal of Pharmacy Research,    (Accepted-sept-2010).

  6. Phytochemical and pharmacological studies of ethanol extract of Anethum graveolens seeds: An approach for the In-vivo Anti-inflammatory, Analgesic and Antipyretic activities

    Mallinath H. Hugara, Kallappa M. Hosamania* and D.K.Sureshb  Phytochemistry, Elsevier Publication, communicated on 06-10-2010.

  7. Synthesis of Bis-Benzimidazoles Efficiently Catalyzed by PTA and their In-Vivo Evaluation for Anti-inflammatory, Analgesic and Anti-pyretic Activities Mallinath H. Hugar, Kallappa M. Hosamani* and Harisha R. Seetharamareddy   Archiv der Pharmazie, Wiley-InterScience Publication, communicated on 06-10-10.

  8. Targeted anti-microbial and cytotoxic studies of novel 4-thiazolidinone and 1, 3, 4-oxadiazole derivatives of 2-mercapto benzimidazole. Ramya V. Shingalapur, K. M. Hosamani*, Rangappa S. Keri and M. H. Hugar International journal of antimicrobial agents , Elsevier Publication, Communicated on 17-11-09.

  9. In-vivo anti-diabetic and anti-convulsant evaluation of 3-benzo [4,5] imidazo [2,1-b]  thiazol-3-ylchromen-2-one derivatives. Harisha R S, Kallappa M Hosamani*, Mallinath H Hugar, European Journal of Medicinal Chemistry, Elsevier Publication, Communicated on 13-03-2010.

  10. Catalytic synthesis of bis-benzimidazole derivatives using phosphotungstic acid (H3PW12O40). Mallinath H Hugar, Kallappa M Hosamani*,; Harisha R S, Synthetic Communications, Taylor & Francis, Communicated on 26-02-2010.

  11. Design, Synthesis, Characterization and Pharmacological Screening Studies of New  Substituted-4-amino benzo quinazoline Derivatives. Mallinath H. Hugar, Kallappa M. Hosamani*  Harisha R. Seetharamareddy European Journal of Medicinal Chemistry, Elsevier Publication, Communicated.

  12. Synthesis, characterization and Pharmacological evaluation of diamagnetic Pd(II) complex derived from 2,6-bis-[5- (3, 4-Dimethoxy-phenyl)-4H-[1,2,4]triazol-3-yl]-pyridine.       Praveen N. Naik,  M. H. Hugar, S. T. Nandibewoor  and S. A. Chimatadar* European Journal of Medicinal Chemistry, Elsevier Publication, Communicated.

  13. Transition metal complexes of thiosemicarbazones with quinoxaline hub: An emphasis on antidiabetic property. Naveen V. Kulkarni, Gurunath S. Kurdekar, Mallinath H. Hugar, Srinivasa Budagumpi, Sathisha M. P. and Vidyanand K. Revankar*   Medicinal Chemistry Research, Springer link publication, communicated.

  14. Synthesis, spectral characterization and antidiabetic studies of transition metal complexes with N2O donor benzimidazole assets. Gurunath S. Kurdekar§, Srinivas Budagumpi§, Mallinath H. Hugar Naveen V. Kulkarni§ and Vidyanand K. Revankar§Industry and Engineering chemistry, Elsevier Publication, communicated.

  15. Synthesis and biological activity of some bis- substituted 1, 3, 4 triazoles and 1, 3, 4 thiadiazoles. S.M.Kudari*,  M.H.Hugar, Raga Basavaraj, Research Journal of Chemistry &Environment, ,5(3),1-4. 2001.

  16. Phytochemical and Analytical studies on the roots of Tecoma stans Linns, K.Durgarao*.  M.H.Hugar 59 th Indian Pharmaceutical Congress. Hyderabad­-2005.(poster).

  17. Improvement in dissolution efficiency and anti-inflammatory activity of poorly Water soluble drug Nabumitone. S.S.Bushetti*, M.H.Hugar. 12th APTI Annual national convention.  Chandigarh , 2007, 25-27.(Scientific Abstract).B-138.

  18. Assessment of Analgesic and Anti-pyretic activities of Dalbergia Sissoo seeds M.H.Hugar* D.K.Suresh, K.Durgarao and Md.Liyakat Ahmed. International Herbal Conference, Bangalore-2009    (Scientific Abstract) SNPS/IHCB/09358.

  19. Efficacy, Safety, Quality control, Marketing and Regulatory guide line for herbal Medicines. M.H.Hugar,  K.Durgarao* International Herbal Conference, Bangalore-2009    (Scientific Abstract) SNPS/IHCB/09584.

 

 

        S. HUMAIRA  

  1. Humaira, A. K. Dey, S. A. Raju, S. Sanaulla. Development and validation of Spectrophotometric methods of amisulpride in pharmaceutical dosage forms. International Journal of chemical sciences, 6(1), 2008, 437-440.
  2. M. A. Saleem, M. Tahera, S. Sanaullah, M. Najamuddin, Javeed Ali, S. Humaira, and S. Roshan. Formulation and evaluation of tramadol hydrochloride rectal suppositories. Indian Journal of Pharmaceutical Sciences 2008; Vol 70, Issue 5, 640-644.
  3. S. Appal Raju, P. N. Sanjay Pai, Khaja Pasha, S. Humaria. Simultaneous estimation of Ofloxacin and Tinidazole by reverse phase high performance chromatography. International Journal of chemical sciences, 6(3), 2008, 1556-1561.
  4. S. Humaria, A.K.Dey, S. A. Raju, S. Sanaulla. Spectrophotometric determination of amisulpride. International Journal of chemical sciences, 7(2), 2009, 912-918.
 

 

        Asgar Ali

  1. Asgar Ali, Khaja Pasha, Dr.S.A.Raju and Syeda Humaira, Visible spectrophotometric determination of amlodipine in pharmaceutical formulation and bulk drug using bromocresol purple, International  journal of chemical sciences, Int.J.Chem.Sci:8(1), 2010, 645-648.

  2. Khaja Pasha, Asgar Ali & Syeda Humaira, Reverse phase hplc method for the analysis of ofloxacin in pharmaceutical dosage form, Journal of chemical and pharmaceutical sciences, volume-3     issue- 1 January -March 2010, pp 52, 53.

  3. Asgar Ali, Khaja Pasha, Dr.S.A.Raju and Aejaz Ahmed, Visible spectrophotometric determination of amlodipine in pharmaceutical formulation and bulk drug using bromophenol blue, International journal pharmacy and pharmaceutical sciences, Volume-2 issue-2 2010,pp 128 – 129.

  4. Khaja Pasha, Asgar Ali & Shahana Banu & Syeda Humaira, Reverse phase – hplc method for the analysis of tinidazole in    pharmaceutical dosage form & bulk drug, International journal pharmacy and pharmaceutical sciences, vol 2 supp 2 2010 ,pp 46,47.

  5. Aejaz ahmed, Asgar ali, formulation and in vitro evaluation of ready use of ampicillin trihydrate, International journal of applied pharmaceutics’, Volume-2 issue-3 2010,pp 27-30.

  6. Ali Sadath, Roshan S,Saleem MA, Patel MJ and Ali Asgar, Effect of abutilon indicom on carbon tetra chloride induced hepatic damage in albino rats, Journal of pharmaceutical research, Vol 3,no.4, October 2004.

  7. syeda Humaira, Akalanka Dey, Appala Raju, Syed Sanaullah, Asgar Ali, & Khaja Pasha, Spectrophotometric determination of amisulpride, Turk j. pharm.sci.69(3)221-230,2009.

  8. M.Najmuddin,Sachin Shelar, Asgar Ali, V.Patel, & T.Khan, Formulation and in vitro evaluation of floating micro spheres of ketoprofen prepared by emulsion solvent diffusion method, International journal pharmacy and pharmaceutical sciences, vol.2 Issue 1, 2010.pp13 - 17.

  9. M.Najmuddin, Vishal Ashok Patel, Asgar Ali, S.Shelar, K.Tousif, Development and evaluation of pulsatile drug  and delivery system of flurbiprofen, Journal of pharmaceutical , biological and chemical sciences, april-June2010 RJPBCS Vol.1 Issue-2, 284-290.

 

        NIKATH   F.  

  1. Nikath F, D. Satyanarayana, Arun B. Joshi. Phytochemical and Pharmacological investigation on roots of Syzygium cumini (L) Skeel. Asian Journal of Research in Chemistry, 2008, (1): 22-25.
  2. Nikath F, D. Satyanarayana, M. G. Purohit. Compiled update on the roots of Syzygium cumini (L) Skeel. Research Journal of Pharmacy and Technology, 2009, 2(1): 138-140.
  3. Nikath F, D. Satyanarayana, Subhramanyam EVS. Isolation and Charecteriztion and screening of Antioxidant activity of the roots of Syzygium cumini (L) Skeel. Asian Journal of Research in Chemistry, 2009.
  4. Nikath F, D. Satyanarayana. Review article on Indian Medicinal plants. Asian Research Journal of Pharmacognosy and Phyto-Chemistry, 2009; (1), 5-10.

 

        SYED SHAKEEL AHMED

    1.   Syed Shakeel Ahamed, Santhosh R, Karjgi, C. C. Simpi, Savitha Sonowane, N. V. Kalyane. Visible spectrophotometric methods for the estimation of Losartan potassium and

          omeprazole in single component pharmaceutical formulation. International Journal of Pharma Tech Research, Vol.1, No.4, pp1247-1250, Oct-Dec 2009.

    2.   Ahmed Syed Shakeel, Kalyane N.V, Karjgi S.R, Ahmed Md.Liyakat  Synthesis and antibacterial activity of new Schiff’s bases International journal of pharmacy and life sciences 

          1(5):Sep.-2010,pp 246-249.

 

        KHAJA PASHA  

  1. P. N. Sanjay Pai, Gopalkrishna Rao, B. Balkrishna, Hamid Khan, and K. Pasha. Spectrophometric method for Determination of Carbocysteine. Indian J. Pharm. Edu. 39 (2) April – June 2005.

    2.   S. Appal Raju, P. N. Sanjay Pai, Khaja Pasha, S. Humaria. Simaltaneous estimation of Ofloxacin and Tinidazole by reverse phase high performance chromatography. International

         Journal of chemical sciences, 6(3), 2008, 1556-1561.