PHARMACEUTICAL
INORGANIC CHEMISTRY – 1st B-Pharm (75
Hours)
First Sessional
|
Sl.No. |
Chapter
No |
Topic |
Sub
Topic |
Hours |
|
01. |
Chapter
No-01 |
Sources
and effect of impurities in pharmacopoeial
substances, important of limit tests, general principles and procedures for
limit tests for chloride, Sulphate, iron, arsenic,
lead and heavy metals. Special procedure for limit tests. |
|
10 Hours |
|
02 |
Chapter
No-04 |
Fundamentals
of volumetric analysis, theory of indicators and method of expressing
concentration. Primary and secondary standard, Preparation standardization
and storage of various volumetric solution like oxalic acid, sodium
hydroxide, hydrochloride acid, sodium thiosulfate, sulphric acid, potassium permanganate, Iodine and Cerric Ammonium Sulphate
solution. |
|
08Hours |
|
|
|
4.2) Theory of nonaqueous
titration |
Classification
of solvents used in nonqueous titration, Estimation
of sodium Benzoate by nonqueous titration. |
04 Hours |
|
|
|
4.3)
Principles of precipitation titration |
Different
methods-Mohr’s, Volhard’s
Modified Volhard’s, Fajans
with example. Estimation of Sodium chloride. |
05 Hours |
Second Sessional
|
Sl.No. |
Chapter
No |
Topic |
Sub
Topic |
Hours |
|
|
|
4.1) Principles of redox
titration’s |
Concept
of oxidation and reducation. Redox
reaction, strength and equivalent weights of oxidizing and reducing agents,
theory of redox titration, cerrimetry,
Iodometry bromometry
titration, with potassium iodate, potassium bromate, titanous chloride,
2,6-dichlorophenol indophenol |
10 Hours |
|
|
|
4.4) Principles of complexometric
titration |
Different
types of complexometric titrations, methods of
detecting the endpoint in complexometric titration
with example. Estimation of calcium Gluconate. |
05 Hours |
|
03 |
Chapter
No-02 |
General
methods of preparation, assay, storage condition & medicinal uses of
inorganic compounds belonging to the following classes. |
2.1) Medicinal Gases: oxygen, Nitrous oxide,
Carbon dioxide 2.2)
Gastrointestinal agents Acidifiers:
dil HCL Antacid:
Aluminium hyroxide gel,
Calcium carbonate, Sod, bicarbonate, Magnesium trisilcate,
Magnesium carbonate (light and heavy)Magnesium
hydroxide mixture and Zinc oxide. Protective and adsorbents:
Kaolin and Talc, Cathartics:
Magnesium Sulphate. Sodium orthophosphate, Sodium Sulphate. |
02 Hours 07 Hours |
Third Sessional
|
Sl.No. |
Chapter
No |
Topic |
Sub
Topic |
Hours |
|
03 |
Continued Chapter
No-02 |
General
methods of preparation, assay, storage condition & medicinal uses of
inorganic compounds belonging to the following classes. |
2.3) Major intra and extra cellular electrolytes, Major
physiological ions and electrolytes used for the replacement therapy,
physiological acid base balance, electrolyte combination therapy ORS, Sodium chloride
injection, Dextroseand Sodium chloride injection,
calcium gluconate injection. 2.4) Topical agents and dermatolgical preparation: Protective:
Tlac, Zinc oxide, Zinc stearat,
Titanium dioxide. Antimicrobials: Potassium Permanganate, Chlorinated lime,
Iodine & its preparation, Boric acid Borax. 2.5) Dental products : Dentifrices, Anticaries agents, Desensitizing agents, calcium
carbonate, sodium fluoride, Stannous fluoride, Zinc chloride, Zinc eugenol cement. 2.6) Miscellaneous agents: Expectorants: Ammonium
chloride (Formal method), Potassium iodide, Haematinic:
Ferrous sulfate, Ferrous gluconate, Ferrous Fumarate, Iron dextran
injection, Iron and Ammaonium citrate. Emetics:
Copper Sulphate. Poision
and antidotes : Sodium thiosulphate, Charcoal, (activated)
Pjharmaceutical Aids: Bentonite,
Sodium metabisulphite, Barium Sulphate |
06 Hours 06 Hours 03 Hours 04 Hours |
|
04 |
Chapter
No-03 |
Sources
of errors, types of errors, methods of minimizing errors, accuracy, precision
& significant figures. |
|
05Hours |