PHARMACEUTICAL
ENGINEERING – 3RD B-Pharm
(75 Hours)
First Sessional
|
Sl.No. |
Chapter
No |
Topic |
Sub
Topic |
Hours |
|
01. |
Chapter
No-01 |
Stoichiometry |
a)
Unit Processes, material and energy balance, units and their conversion
Dimensional formulae, dimensionless numbers.. |
(02Hours) |
|
02. |
Chapter
No-02 |
Size
reduction |
Definition,
objectives of size reduction, factors affecting size reduction, laws governing
energy and power requirements of a mill types of mills, construction and
working of ball mill, hammer mill, fluid energy mill, Edge runner mill. |
(03Hours) |
|
03. |
Chapter
No-03 |
Size
Separation |
Different
techniques of size separation-sieve shakers, sedimentation tanks, Mechanical
classifiers, Cyclone separators, Bag Filter. |
(03Hours) |
|
04. |
Chapter
No-04 |
Mixing |
Theory
of mixing, solid-solid, solid-liquid-liquid mixing. Equipment-tumbler,
V-cone, double cone, ribbon blenders, Sigma blade and planetary, zigzag
mixers, Mixing devices, Propellers, turbines, paddles and baffles. Vortex
formation and prevention. Homogenization, and homogenizers. |
(06Hours) |
|
05. |
Chapter
No-05 |
Drying |
Moisture
content and mechanism of drying factors affecting drying. Classification and
types of dryers, dryers used in pharmaceutical industries. Construction and
working of tray dryers, fluidized bed dryer, drum dryer, vacuum Dryer, Freeze
dryer and Spray dryer. |
(05Hours) |
|
06. |
Chapter
No-06 |
Filtration
and centrifugation |
Theory
of filtration and Kozeny’s equation, classification
of industrial filters, Construction and working of filter press, filter leaf,
meta filter candle filter. Filter aids. Theory and principle of
centrifugation, classification of industrial centrifuges,
Centrifuges,-basket, tubular bowl, conical disc, semi continuous horizontal
centrifuges. |
(05Hours) |
Second Sessional
|
01. |
Chapter
No-01 |
Evaporation |
Basic
concept of phase equilibria, factors affecting
evaporation Evaporators,-film evaporators, single effect and multiple effect
evaporators, theory and economy. |
(05Hours) |
|
02. |
Chapter
No-02 |
Distillation |
Raoult’s law, Volatility, simple,
steam and flash distillations. Principles of rectification, azeotropic, molecular and extractive distillation. |
(06Hours) |
|
03. |
Chapter
No-03 |
Crystallization |
|
(06Hours) |
|
04. |
Chapter
No-04 |
Material
Handling system |
Construction
and working of a belt conveyor, screw conveyor, pneumatic conveyor, cycloidal blowers and chain conveyors. |
(05Hours) |
|
05. |
Chapter
No-05 |
Materials
of construction |
Iron,
Steel, lead, glass, aluminium, rubber and plastic
as construction materials. |
(05Hours) |
Third Sessional
|
01. |
Chapter
No-02 |
Fluid
flow |
a)
Fluid statics: hydrostatics pressure, definition of heads, manometers. b)
Fluid dynamics: mechanism of fluid flow, Reynolds experiment, Bernoulli’s theorem
and its application, Flow meters-, orifice meter, venture meter, pitot tube and rotameter. |
(06Hours) |
|
02. |
Chapter
No-03 |
Heat
transfer |
Concept
of heat by conduction through single wall, application of Fourier’s law. Forced
and natural convection surface coefficients, Boiling liquids, Condensing
vapors, Temperature gradients in parallel and counter current heat
exchangers. Heat interchangers, Radiation, black body, Stefan-Boltzmann
equation, Kirchoff’s law. |
(06Hours) |
|
03. |
Chapter
No-04 |
Humidification,
Air-conditioning Refrigeration. |
Definition
of humidity, humid heat, humid volume, study of psychometric charts, wet bulb
theory, theory of air conditioning and air conditioner. Refrigerator, single stage
refrigeration, Mollier’s diagram, coefficient of
performance, and their application to pharmacy. |
(06Hours) |
|
04. |
Chapter
No-05 |
Corrosion |
Classification
and mechanism of corrosion, Factors, Prevention and control. |
(03Hours) |
|
05. |
Chapter
No-06 |
Plant
location |
Layout,
utilities and services. Industrial hazards and safety measures. |
(03Hours) |